The highly controlled environments that genetically engineered formulas are created in mean that there is little to no concern regarding unwanted pesticides and irritants. These are often found in nature and may contribute to product predictability. For example, those with sensitive skin types may be more susceptible to possible redness and irritation if the product they use has varied slightly from the previous formula.

However, biotechnology is about more than predictability— it's also about sustainability. Peptides and proteins form the cornerstone of high-quality skincare and using natural substances such as fungi to produce these make a substantial impact on the production process's carbon footprint. Biotechnology doesn't require the land, water, or resources that botanical ingredients do.

In using far less of these resources, companies that produce biotech skincare products allow nature to carry on as it usually would, reducing their impact on the natural environment and the animals that rely on it.